Leon H Mullenders: search on Z-Library

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1

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: Impact on DNA repair and UV-induced skin cancer

Alex Pines, Claude Backendorf, Sergey Alekseev, Jacob G. Jansen, Frank R. de Gruijl, Harry Vrieling, Leon H.F. Mullenders

Journal:

Year:

2009

Language:

english

File:

PDF, 785 KB

english, 2009

2

Gene and sequence specificity of DNA damage induction and repair: consequences for mutagenesis

Albert A. van Zeeland, Leon H.F. Mullenders, Harry Vrieling

Journal:

Mutation Research/DNA Repair

Year:

2001

Language:

english

File:

PDF, 66 KB

english, 2001

3

Impact of arsenic on nucleotide excision repair: XPC function, protein level, and gene expression

Maike Nollen, Franziska Ebert, Jill Moser, Leon H. F. Mullenders, Andrea Hartwig, Tanja Schwerdtle

Journal:

Molecular Nutrition & Food Research

Year:

2009

Language:

english

File:

PDF, 727 KB

english, 2009

4

Electrochemical Detection and Quantification of the Acetylated and Deacetylated C8-Deoxyguanosine DNA Adducts Induced by 2-Acetylaminofluorene

Sandra A.M. Bol, Anton J.L. de Groot, Roeline B. Tijdens, John H.N. Meerman, Leon H.F. Mullenders, Albert A. van Zeeland

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 137 KB

english, 1997

5

Nucleotide excision repair and its interplay with transcription

Anneke van Hoffen, A.S Balajee, Albert A van Zeeland, Leon H.F Mullenders

Journal:

Year:

2003

Language:

english

File:

PDF, 213 KB

english, 2003

6

UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer

Frank R de Gruijl, Henk J van Kranen, Leon H.F Mullenders

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

7

Photoimmunology and nucleotide excision repair: impact of transcription coupled and global genome excision repair

Leon H.F Mullenders, Mark Berneburg

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2001

Language:

english

File:

PDF, 52 KB

english, 2001

8

Disruption of DNA repair processes by carcinogenic metal compounds

Andrea Hartwig, Leon Mullenders, Monika Asmuß, Heike Dally, M. Hartmann

Journal:

Analytical and Bioanalytical Chemistry

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998

9

Defective Global Genome Repair in XPC Mice Is Associated with Skin Cancer Susceptibility But Not with Sensitivity to UVB Induced Erythema and Edema

Berg, Rob J. W., Ruven, Hendrik J. T., Sands, Arthur T., de Gruijl, Frank R., Mullenders, Leon H. F.

Journal:

The Journal of Investigative Dermatology

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

10

Enhanced Nucleotide Excision Repair in Human Fibroblasts Pre-exposed to Ionizing Radiation

Patricia Cramers, Alfred Ronald Filon, Alex Pines, Jos C. Kleinjans, Leon H. F. Mullenders, Albert A. van Zeeland

Journal:

Photochemistry and Photobiology

Year:

2012

Language:

english

File:

PDF, 458 KB

english, 2012

11

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

Fousteri, Maria, Mullenders, Leon HF

Journal:

Year:

2008

Language:

english

File:

PDF, 806 KB

english, 2008

12

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Garinis, George A., Uittenboogaard, Lieneke M., Stachelscheid, Heike, Fousteri, Maria, van Ijcken, Wilfred, Breit, Timo M., van Steeg, Harry, Mullenders, Leon H. F., van der Horst, Gijsbertus T. J., B

Journal:

Nature Cell Biology

Year:

2009

Language:

english

File:

PDF, 2.31 MB

english, 2009

13

Assessing cancer risks of low-dose radiation

Mullenders, Leon, Atkinson, Mike, Paretzke, Herwig, Sabatier, Laure, Bouffler, Simon

Journal:

Nature Reviews Cancer

Year:

2009

Language:

english

File:

PDF, 333 KB

english, 2009

14

Age-dependent spontaneous mutagenesis in Xpc mice defective in nucleotide excision repair

Wijnhoven, Susan WP, Kool, Hanneke JM, Mullenders, Leon HF, van Zeeland, Albert A, Friedberg, Errol C, van der Horst, Gijsbertus TJ, van Steeg, Harry, Vrieling, Harry

Journal:

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

15

Mouse mismatch repair gene Msh2 is not essential for transcription-coupled repair of UV-induced cyclobutane pyrimidine dimers

Sonneveld, Edwin, Vrieling, Harry, Mullenders, Leon HF, van Hoffen, Anneke

Journal:

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

16

Sealing of Chromosomal DNA Nicks during Nucleotide Excision Repair Requires XRCC1 and DNA Ligase IIIα in a Cell-Cycle-Specific Manner

Jill Moser, Hanneke Kool, Ioannis Giakzidis, Keith Caldecott, Leon H.F. Mullenders, Maria I. Fousteri

Journal:

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

17

Hierarchies of DNA repair in mammalian cells: biological consequences

Leon H.F. Mullenders, Harry Vrieling, Jaap Venema, Albert A. van Zeeland

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1991

Language:

english

File:

PDF, 430 KB

english, 1991

18

Identification of Conserved Pathways of DNA-Damage Response and Radiation Protection by Genome-Wide RNAi

Gijs van Haaften, Ron Romeijn, Joris Pothof, Wouter Koole, Leon H.F. Mullenders, Albert Pastink, Ronald H.A. Plasterk, Marcel Tijsterman

Journal:

Current Biology

Year:

2006

Language:

english

File:

PDF, 546 KB

english, 2006

19

Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

Giel Hendriks, Fabienne Calléja, Ahmad Besaratinia, Harry Vrieling, Gerd P. Pfeifer, Leon H.F. Mullenders, Jacob G. Jansen, Niels de Wind

Journal:

Current Biology

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

20

Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells

Joanne G.W. Nijhof, Aat M. Mulder, Ewoud N. Speksnijder, Esther M. Hoogervorst, Leon H.F. Mullenders, Frank R. de Gruijl

Journal:

Year:

2007

Language:

english

File:

PDF, 966 KB

english, 2007

21

Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells

Giel Hendriks, Fabienne Calléja, Harry Vrieling, Leon H.F. Mullenders, Jacob G. Jansen, Niels de Wind

Journal:

Year:

2008

Language:

english

File:

PDF, 800 KB

english, 2008

22

Transcription factor IIS impacts UV-inhibited transcription

Anne Jensen, Leon H.F. Mullenders

Journal:

Year:

2010

Language:

english

File:

PDF, 894 KB

english, 2010

23

DNA damage response and transcription

Saskia Lagerwerf, Mischa G. Vrouwe, René M. Overmeer, Maria I. Fousteri, Leon H.F. Mullenders

Journal:

Year:

2011

Language:

english

File:

PDF, 701 KB

english, 2011

24

UVA1 radiation inhibits calcineurin through oxidative damage mediated by photosensitization

Ruben E.A. Musson, Paul J. Hensbergen, Adrie H. Westphal, Wouter P.M. Temmink, André M. Deelder, Johannes van Pelt, Leon H.F. Mullenders, Nico P.M. Smit

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 793 KB

english, 2011

25

Meeting Report: EU–US Workshop on Molecular Signatures of DNA damage-induced Stress Responses: Cortona, Italy, 26–30 September 2003

Miriam Sander, Christian Desaintes, Richard Pelroy, Wouter Ferro, Bennett Van Houten, Sally Amundson, Alan Lehmann, Leon Mullenders, Susanna-Assunta Sansone, Peter Stambrook, Bert van Zeeland, Harry V

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2004

Language:

english

File:

PDF, 1.84 MB

english, 2004

26

Transcription-coupled repair: Impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors

Albert A. van Zeeland, Maaike P.G. Vreeswijk, Frank R. de Gruijl, Henk J. van Kranen, Harry Vrieling, Leon F.H. Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

27

Second EU-US workshop on systems level understanding of DNA damage responses

Miriam Sander, Christian Desaintes, Wouter Ferro, Leon Mullenders, Richard Pelroy, Bennett Van Houten, Harry Vrieling, Susan Wallace

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 1.40 MB

english, 2006

28

Nucleotide excision repair in differentiated cells

Caroline van der Wees, Jacob Jansen, Harry Vrieling, Arnoud van der Laarse, Albert Van Zeeland, Leon Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

29

Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea

Albert A. van Zeeland, Anton J.L. de Groot, Georges R. Mohn, Harry van Steeg, Conny van Oostrom, Anne-Marie van Duijn-Goedhart, Leon F.H. Mullenders, Jacob G. Jansen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2008

Language:

english

File:

PDF, 455 KB

english, 2008

30

Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra

Maaike P.G. Vreeswijk, Caro M. Meijers, Micheline Giphart-Gassler, Harry Vrieling, Albert A. van Zeeland, Leon H.F. Mullenders, Wil A.M. Loenen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2009

Language:

english

File:

PDF, 750 KB

english, 2009

31

Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability

Godelieve Smeenk, Anton J.L. de Groot, Ron J. Romeijn, Paul P.W. van Buul, Malgorzata Z. Zdzienicka, Leon H.F. Mullenders, Albert Pastink, Barbara C. Godthelp

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

32

3rd US–EU Workshop: Systems level understanding of DNA damage responses

Miriam Sander, Thomas J. Begley, Christian Desaintes, Anne-Claude Gavin, Richard Pelroy, Joris Pothof, Yosef Shiloh, Dik van Gent, Ben Van Houten, Michael Yaffe, Leon Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

33

Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment

Giel Hendriks, Mirna Atallah, Martine Raamsman, Bruno Morolli, Haidy van der Putten, Haziz Jaadar, Ine Tijdens, Rebecca Esveldt-van Lange, Leon Mullenders, Bob van de Water, Harry Vrieling

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

34

Effects of arsenite and UVA-1 radiation on calcineurin signaling

Ruben E.A. Musson, Leon H.F. Mullenders, Nico P.M. Smit

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

35

The role of XPC: Implications in cancer and oxidative DNA damage

Joost P.M. Melis, Mirjam Luijten, Leon H.F. Mullenders, Harry van Steeg

Journal:

Mutation Research/Reviews in Mutation Research

Year:

2011

Language:

english

File:

PDF, 882 KB

english, 2011

36

Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice

Harry van Steeg, Leon H.F Mullenders, Jan Vijg

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2000

Language:

english

File:

PDF, 603 KB

english, 2000

37

Characterization of defective nucleotide excision repair in XPC mutant mice

David L Cheo, Hendrick J.T Ruven, Lisiane B Meira, Robert E Hammer, Dennis K Burns, Nancy J Tappe, Albert A van Zeeland, Leon H.F Mullenders, Errol C Friedberg

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 486 KB

english, 1997

38

O V A.4 - O V A.4 Processing of structurally different DNA lesions by nucleotide excision repair

Leon H.F. Mullenders, Anneke van Hoffen, Michiel Oosterwijk, Maaike Vreeswijk, Harry Vrieling, A.T. Natarajan, Albert A. van Zeeland

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

39

P V.13 - P V.13 Chromosomal distribution of genes subject to transcription coupled DNA repair

Jordi Surralles, Parimal Karmakar, A.T. Natarajan, Leon H.F. Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 233 KB

english, 1997

40

P VII.2 - P VII.2 Expression of p53 by hepatocarcinogens and non- hepatocarcinogens and its role in tumour promotion

Hilde van Gijssel, Ulla Stenius, Leon Mullenders, John Meerman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 130 KB

english, 1997

41

Transcription coupled repair and its impact on mutagenesis

Harry Vrieling, Albert A. van Zeeland, Leon H.F. Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1998

Language:

english

File:

PDF, 96 KB

english, 1998

42

Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation

Marjan Boerma, Caroline GC van der Wees, Harry Vrieling, J Peter Svensson, Jan Wondergem, Arnoud van der Laarse, Leon HF Mullenders, Albert A van Zeeland

Journal:

Year:

2005

Language:

english

File:

PDF, 638 KB

english, 2005

43

Pre-exposure to Low Doses: Modulation of X-Ray-Induced DNA Damage and Repair?

Cramers, Patricia, Atanasova, Petya, Vrolijk, Hans, Darroudi, Firouz, van Zeeland, Albert A., Huiskamp, René, Mullenders, Leon H. F., Kleinjans, Jos C. S.

Journal:

Radiation Research

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

44

Deficient global genome repair of UV-induced cyclobutane pyrimidine dimers in terminally differentiated myocytes and proliferating fibroblasts from the rat heart

Caroline G.C van der Wees, Maaike P.G Vreeswijk, Marion Persoon, Arnoud van der Laarse, Albert A van Zeeland, Leon H.F Mullenders

Journal:

Year:

2003

Language:

english

File:

PDF, 259 KB

english, 2003

45

Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae

Marcin M Gorski, Ron J Romeijn, Jan C.J Eeken, Anja W.M de Jong, Bert L van Veen, Karoly Szuhai, Leon H Mullenders, Wouter Ferro, Albert Pastink

Journal:

Year:

2004

Language:

english

File:

PDF, 550 KB

english, 2004

46

XPC lymphoblastoid cells defective in the hMutSα DNA mismatch repair complex exhibit normal sensitivity to UVC radiation and normal transcription-coupled excision repair of DNA cyclobutane pyrimidine dimers

Katsutoshi Kobayashi, Mark O’Driscoll, Peter Macpherson, Leon Mullenders, Maaike Vreeswijk, Peter Karran

Journal:

Year:

2004

Language:

english

File:

PDF, 362 KB

english, 2004

47

Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes

Marijke van Oosten, Gerdine J Stout, Claude Backendorf, Heggert Rebel, Niels de Wind, Firouz Darroudi, Henk J van Kranen, Frank R de Gruijl, Leon HF Mullenders

Journal:

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

48

The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions

Jill Moser, Marcel Volker, Hanneke Kool, Sergei Alekseev, Harry Vrieling, Akira Yasui, Albert A. van Zeeland, Leon H.F. Mullenders

Journal:

Year:

2005

Language:

english

File:

PDF, 424 KB

english, 2005

49

Selective DNA damage responses in murine Xpa−/−, Xpc−/− and Csb−/− keratinocyte cultures

Gerdine J. Stout, Marijke van Oosten, Fatima Z. Acherrat, Jan de Wit, Wilbert P. Vermeij, Leon H.F. Mullenders, Frank R. de Gruijl, Claude Backendorf

Journal:

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

50

Repair of DNA lesions in chromosomal DNA: Impact of chromatin structure and Cockayne syndrome proteins

Maria Fousteri, Anneke van Hoffen, Hana Vargova, Leon H.F. Mullenders

Journal:

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

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